Anzio to Rome trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Villa Claudia and arrive at Roma Termini every about 2 hours on average. If travelling with Trenitalia, you need to know the Anzio to Rome train schedule: the first train leaves at 13:23, while the last ride is at 22:13. A Anzio to Rome train cost about 3.6 €. But how long is the train ride from Anzio to Rome? Your journey takes about 1 hour on average. Trenitalia offers 6 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Anzio to Rome and find low cost tickets starting from 2 €!