Brescia to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brescia and arrive at Castelvetrano every about 3 hours on average. If travelling with Trenitalia, you need to know the Brescia to Castelvetrano train schedule: the first train leaves at 17:25, while the last ride is at 18:39. A Brescia to Castelvetrano train cost about 157.45 €. But how long is the train ride from Brescia to Castelvetrano? Your journey takes about 14 hours on average.