Brindisi to Avezzano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Avezzano every about 2 hours on average. If travelling with Trenitalia, you need to know the Brindisi to Avezzano train schedule: the first train leaves at 04:00, while the last ride is at 22:55. A Brindisi to Avezzano train cost about 37.0 €. But how long is the train ride from Brindisi to Avezzano? Your journey takes about 8 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Brindisi to Avezzano and find low cost tickets starting from 29 €!