Casarano to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lecce and arrive at Siracusa, Brindisi every 60 minutes on average. If travelling with Trenitalia, you need to know the Casarano to Syracuse train schedule: the first train leaves at 05:48, while the last ride is at 19:55. A Casarano to Syracuse train cost about 10 €. But how long is the train ride from Casarano to Syracuse? Your journey takes about 2 hours on average.