Caserta to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caserta and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Caserta to Niscemi train schedule: the first train leaves at 09:10, while the last ride is at 12:22. A Caserta to Niscemi train cost about 62.05 €. But how long is the train ride from Caserta to Niscemi? Your journey takes about 15 hours on average.