Castelvetrano to Genoa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Castelvetrano and arrive at Genova Piazza Principe every about 4 hours on average. If travelling with Trenitalia, you need to know the Castelvetrano to Genoa train schedule: the first train leaves at 07:01, while the last ride is at 17:09. A Castelvetrano to Genoa train cost about 76.65 €. But how long is the train ride from Castelvetrano to Genoa? Your journey takes about 23 hours on average.