Desenzano del Garda to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Desenzano del Garda-Sirmione and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Desenzano del Garda to Syracuse train schedule: the first train leaves at 06:05, while the last ride is at 22:51. A Desenzano del Garda to Syracuse train cost about 123.25 €. But how long is the train ride from Desenzano del Garda to Syracuse? Your journey takes about 19 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Desenzano del Garda to Syracuse and find low cost tickets starting from 59 €!