Frosinone to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frosinone and arrive at Mazara del Vallo every about 4 hours on average. If travelling with Trenitalia, you need to know the Frosinone to Mazara del Vallo train schedule: the first train leaves at 10:02, while the last ride is at 20:23. A Frosinone to Mazara del Vallo train cost about 91.0 €. But how long is the train ride from Frosinone to Mazara del Vallo? Your journey takes about 21 hours on average.