Grottaferrata to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Frascati and arrive at Messina Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Grottaferrata to Messina train schedule: the first train leaves at 06:35, while the last ride is at 21:36. A Grottaferrata to Messina train cost about 63.1 €. But how long is the train ride from Grottaferrata to Messina? Your journey takes about 9 hours on average.