Melzo to Novi Ligure trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Melzo and arrive at Novi Ligure every 60 minutes on average. If travelling with Trenitalia, you need to know the Melzo to Novi Ligure train schedule: the first train leaves at 06:29, while the last ride is at 19:59. A Melzo to Novi Ligure train cost about 10.95 €. But how long is the train ride from Melzo to Novi Ligure? Your journey takes about 3 hours on average.