Mentana to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Monterotondo-Mentana, Roma Termini and arrive at Palermo Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the Mentana to Palermo train schedule: the first train leaves at 06:32, while the last ride is at 22:26. A Mentana to Palermo train cost about 49.90 €. But how long is the train ride from Mentana to Palermo? Your journey takes about 12 hours on average. Trenitalia offers 2 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Mentana to Palermo and find low cost tickets starting from 29 €! When booking your train ticket a few weeks in advance though, you can find low cost trains from Mentana to Palermo with fares starting from 27.90€, saving up to 43%.