Milan to Florence trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Milano Centrale and arrive at Firenze S. M. Novella every 60 minutes on average. If travelling with Trenitalia, you need to know the Milan to Florence train schedule: the first train leaves at 05:42, while the last ride is at 20:15. A Milan to Florence train cost about 25.90 €. But how long is the train ride from Milan to Florence? Your journey takes about 2 hours on average. Trenitalia offers 17 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Milan to Florence and find low cost tickets starting from 9 €! If you need to travel this week, prices start from 35.90€ to a maximum price of 56.00€. When booking your train ticket a few weeks in advance though, you can find low cost trains from Milan to Florence with fares starting from 11.40€, saving up to 74%.