Milan to Senigallia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed , since many high speed Trenitalia trains are available on this route , as well as Intercity, Trenitalia, Frecciabianca, Regionale Veloce, InterCityNotte trains . You can count on 21 daily rides to get from Milan to Senigallia. Trains leave from Milano Centrale and arrive at Senigallia, Firenze S. M. Novella every 60 minutes on average. If travelling with Trenitalia, you need to know the Milan to Senigallia train schedule: the first train leaves at 05:42, while the last ride is at 21:10. A Milan to Senigallia train cost about 19 €. But how long is the train ride from Milan to Senigallia? Your journey takes about 4 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Milan to Senigallia and find low cost tickets starting from 7 €!