Molfetta to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Molfetta and arrive at Caltanissetta Centrale every about 12 hours on average. If travelling with Trenitalia, you need to know the Molfetta to Caltanissetta train schedule: the first train leaves at 16:23, while the last ride is at 16:23. A Molfetta to Caltanissetta train cost about 101.2 €. But how long is the train ride from Molfetta to Caltanissetta? Your journey takes about 19 hours on average.