Nettuno to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Nettuno and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Nettuno to Messina train schedule: the first train leaves at 09:07, while the last ride is at 20:07. A Nettuno to Messina train cost about 42.6 €. But how long is the train ride from Nettuno to Messina? Your journey takes about 11 hours on average.