Niscemi to Como trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Niscemi and arrive at Como S. Giovanni every about 6 hours on average. If travelling with Trenitalia, you need to know the Niscemi to Como train schedule: the first train leaves at 06:22, while the last ride is at 18:08. A Niscemi to Como train cost about 176.1 €. But how long is the train ride from Niscemi to Como? Your journey takes about 11 hours on average.