Pistoia to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pistoia and arrive at Castelvetrano every about 6 hours on average. If travelling with Trenitalia, you need to know the Pistoia to Castelvetrano train schedule: the first train leaves at 18:12, while the last ride is at 20:44. A Pistoia to Castelvetrano train cost about 89.85 €. But how long is the train ride from Pistoia to Castelvetrano? Your journey takes about 21 hours on average.