Potenza to Sienna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Potenza Superiore and arrive at Siena every about 12 hours on average. If travelling with Trenitalia, you need to know the Potenza to Sienna train schedule: the first train leaves at 22:05, while the last ride is at 22:05. A Potenza to Sienna train cost about 99.4 €. But how long is the train ride from Potenza to Sienna? Your journey takes about 12 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Potenza to Sienna and find low cost tickets starting from 30 €!