Sienna to Caserta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Caserta every 60 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Caserta train schedule: the first train leaves at 05:55, while the last ride is at 15:18. A Sienna to Caserta train cost about 67.53 €. But how long is the train ride from Sienna to Caserta? Your journey takes about 6 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sienna to Caserta and find low cost tickets starting from 28 €!