Syracuse to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siracusa and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Syracuse to Palermo train schedule: the first train leaves at 06:32, while the last ride is at 13:00. A Syracuse to Palermo train cost about 14.5 €. But how long is the train ride from Syracuse to Palermo? Your journey takes about 8 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Syracuse to Palermo and find low cost tickets starting from 15 €!